Lindsay Marshall, PhD, is Biomedical Science Advisor at the Humane Society of the United States and Humane Society International (HSUS/HSI). She is a Fellow of the Royal Society of Biology in the UK and a Senior Fellow of the Higher Education Academy. Prior to her current position, Lindsay spent around 12 years at Aston University in the UK. As Senior Lecturer in Immunology, she incorporated a strong element of animal replacement in all of her teaching. She was winner of the student-led ‘Astonishing Academic’ award for three consecutive years. Her research programme during her time in academia was dedicated to the theme of human respiratory defences, where she ultimately developed multi-cellular human cell-based models of human airways. Her models of healthy human airways were used to examine the potentially toxic effects of e-cigarette vapour on human lungs, and she also created models of cystic fibrosis airways, which were used to evaluate possible treatments for infections
in people with cystic fibrosis.
She is now the European Advisor for the BioMed21 Collaboration, an initiative that brings together scientists from across Europe, Asia and the Americas with a shared vision of a new, human-focused paradigm for health research. As part of this position, her key activities are to liaise with academics to develop critical reviews of animal disease models, and support HSI-HSUS public policy efforts through the preparation of targeted briefing materials for politicians and other non-expert stakeholders. In 2018, she reviewed the use of non-animal models used in respiratory tract disease research for a collaboration between the chemical consultancy EcoMole, Prof Ian Adcock of Imperial College London and the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM). The ultimate aim of this research is to develop a freely available database of non-animal methods which scientists could access in order to help them make decisions regarding the use of these
innovative human relevant techniques in their research. Other projects are creating databases for common human diseases like neurodegenerative conditions (such as Parkinson’s Disease and Alzheimer’s Disease), breast cancer, autoimmune diseases and cardiovascular diseases.
Along with several academic colleagues, she is currently working on a project to produce an animal-free curriculum – creating educational materials that will allow scientists, students, lawmakers, funders and other interested parties, to design and execute their research projects without using animals, as there are currently few courses that help and encourage people to carry out animal-free research.